TopTechTrends

The Download: the case for AI slop, and helping CRISPR fulfill its promise

January 9, 2026
This is today’s edition of The Download, our weekday newsletter that provides a daily dose of what’s going on in the world of technology. How I learned to stop worrying and love AI slop —Caiwei Chen If I were to locate the moment AI slop broke through into popular consciousness, I’d pick the video of rabbits bouncing…

A new CRISPR startup is betting regulators will ease up on gene-editing

January 9, 2026
Here at MIT Technology Review we’ve been writing about the gene-editing technology CRISPR since 2013, calling it the biggest biotech breakthrough of the century. Yet so far, there’s been only one gene-editing drug approved. It’s been used commercially on only about 40 patients, all with sickle-cell disease. It’s becoming clear that the impact of CRISPR…

GTMfund has rewritten the distribution playbook for the AI era

January 8, 2026
Building software products has never been easier, so why are so many well-funded startups failing to take off no matter how good their product is? In this season finale episode of Build Mode, our guest has an answer: Startups have focused too much on product development and not enough on distribution excellence. Paul Irving is partner and […]